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SAT1 and MTA1
Data Source:
BioGRID
(two hybrid)
SAT1
MTA1
Description
spermidine/spermine N1-acetyltransferase 1
metastasis associated 1
Image
GO Annotations
Cellular Component
Cytosol
Nucleus
Nuclear Envelope
Nucleoplasm
Cytoplasm
Cytosol
Microtubule
NuRD Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Diamine N-acetyltransferase Activity
Protein Binding
N-acetyltransferase Activity
Spermidine Binding
Identical Protein Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Repressing Transcription Factor Binding
Chromatin Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Zinc Ion Binding
Histone Deacetylase Binding
Biological Process
Angiogenesis
Polyamine Biosynthetic Process
Putrescine Catabolic Process
Spermidine Acetylation
Negative Regulation Of Transcription By RNA Polymerase II
Double-strand Break Repair
Signal Transduction
Response To Ionizing Radiation
Histone Deacetylation
Circadian Regulation Of Gene Expression
Regulation Of Gene Expression, Epigenetic
Entrainment Of Circadian Clock By Photoperiod
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Locomotor Rhythm
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Autoubiquitination
Pathways
Interconversion of polyamines
HDACs deacetylate histones
SUMOylation of transcription factors
ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression
RNA Polymerase I Transcription Initiation
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Potential therapeutics for SARS
Drugs
N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases
Keratosis follicularis spinulosa decalvans
GWAS
Heel bone mineral density (
30598549
)
Interacting Genes
98 interacting genes:
ABCB8
ABHD15
APLP1
B4GALT3
BHLHA9
C19orf25
CASP7
CCDC148
CCDC90B
CCHCR1
CDC42EP1
CEP126
CHD3
COPS6
COX6C
CRMP1
CSNK2A1
CSNK2A2
DDX39A
DGKZ
DIPK1B
DMRT3
DNPEP
EEF1G
EIF3D
EPHB6
ERG28
EVA1A
FAM156A
FAM228A
FAM86C1P
FH
FTSJ3
FUNDC2
GAS2L2
GBP2
GDF9
HIF1A
HOXB6
HOXB9
HSPB1
HSPE1
INO80C
ITGA9
JUNB
KAT5
KAT7
KCNA4
KHDC4
LHX3
LNX1
LRIF1
LUC7L2
LYRM7
MED31
MEOX2
MRPL12
MRPL9
MTA1
MYPOP
NIF3L1
NMRK2
NTAQ1
PLGRKT
PRDX2
PSMA1
PTN
RACK1
RBM17
RBM48
REL
RELA
RPLP1
RPP25
SARAF
SAT2
SEPHS1
SETDB1
SNAI2
TACO1
TCF25
TEAD4
TEX43
TLE1
TLE5
TNNI1
TP53
TP53TG1
TSC22D4
TUBB2A
TXN2
UBE2D3
UNC119
USHBP1
UTP14A
VASP
VKORC1
ZHX1
45 interacting genes:
BCL11A
BLOC1S1
CCNH
CSNK1G2
CYSRT1
DDX18
DYNLL1
E2F1
ERCC6
ESR1
FHL3
GPR183
GRB2
H3-4
HDAC1
HDAC2
HIF1A
ITGB3BP
JUN
KHDRBS2
KPNA4
KRT31
KRT40
KRTAP10-8
LMO4
LRRK2
LZTS2
MAGEA11
MBD3L2
MNAT1
NACC2
NBPF19
NELFCD
NOTCH2NLA
PICK1
PLEKHG4
RBBP4
SAT1
SH3GL1
SH3GLB1
SUMO2
TEX11
TP53
TRIM25
UBE2I
Entrez ID
6303
9112
HPRD ID
02431
04633
Ensembl ID
ENSG00000130066
ENSG00000182979
Uniprot IDs
A0A384NQ10
P21673
Q13330
Q9BRL8
PDB IDs
2B3U
2B3V
2B4B
2B4D
2B58
2B5G
2F5I
2FXF
2G3T
2JEV
4BKX
4PBY
4PBZ
4PC0
5FXY
5ICN
6G16
Enriched GO Terms of Interacting Partners
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