BDKRB1 and SLC44A2

Data Source:
BioGRID (two hybrid)

		BDKRB1	SLC44A2
Description		bradykinin receptor B1	solute carrier family 44 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Choline Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Phosphatidylcholine Biosynthetic Process Choline Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Transmembrane Transport
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Synthesis of PC Transport of bile salts and organic acids, metal ions and amine compounds Neutrophil degranulation
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	Bipolar disorder ( 31043756) Height ( 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Ischemic stroke ( 29531354) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 24076602) Platelet count ( 29403010 32888494) Platelet distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Stroke ( 29531354) Thrombosis ( 26908601) Venous thromboembolism ( 25772935 31676865)
Interacting Genes		32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	2 interacting genes: BDKRB1 HTR2B
Entrez ID		623	57153
HPRD ID		02639	16198
Ensembl ID		ENSG00000100739	ENSG00000129353
Uniprot IDs		P46663	A0A088QCU6 Q8IWA5
PDB IDs
Enriched GO Terms of Interacting Partners?
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