SLC44A2 and BDKRB1

Data Source:
BioGRID (two hybrid)

		SLC44A2	BDKRB1
Description		solute carrier family 44 member 2	bradykinin receptor B1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Integral Component Of Membrane Specific Granule Membrane Extracellular Exosome	Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Neuron Projection
	Molecular Function	Choline Transmembrane Transporter Activity Transmembrane Transporter Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Phosphatidylcholine Biosynthetic Process Choline Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Transmembrane Transport	Negative Regulation Of Protein Phosphorylation Positive Regulation Of Leukocyte Migration Inflammatory Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Response To Mechanical Stimulus Cell Migration Sensory Perception Of Pain Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Synthesis of PC Transport of bile salts and organic acids, metal ions and amine compounds Neutrophil degranulation	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs			Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 31043756) Height ( 31562340) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Ischemic stroke ( 29531354) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 24076602) Platelet count ( 29403010 32888494) Platelet distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Stroke ( 29531354) Thrombosis ( 26908601) Venous thromboembolism ( 25772935 31676865)	Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: BDKRB1 HTR2B	32 interacting genes: C1orf43 CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		57153	623
HPRD ID		16198	02639
Ensembl ID		ENSG00000129353	ENSG00000100739
Uniprot IDs		A0A088QCU6 Q8IWA5	P46663
PDB IDs
Enriched GO Terms of Interacting Partners?
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