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RPGR and ATP6AP2
Data Source:
HPRD
(two hybrid)
RPGR
ATP6AP2
Description
retinitis pigmentosa GTPase regulator
ATPase H+ transporting accessory protein 2
Image
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Golgi Apparatus
Centrosome
Ciliary Basal Body
Sperm Flagellum
Autophagosome Membrane
Lysosome
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Plasma Membrane
External Side Of Plasma Membrane
Endosome Membrane
Integral Component Of Membrane
Apical Plasma Membrane
Vacuolar Proton-transporting V-type ATPase Complex
Axon
Dendritic Spine Membrane
Cell Body
Postsynaptic Membrane
Extracellular Exosome
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Molecular Function
RNA Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Protein Binding
Signaling Receptor Activity
Biological Process
Intracellular Protein Transport
Visual Perception
Intraciliary Transport
Regulation Of Catalytic Activity
Response To Stimulus
Cilium Assembly
Angiotensin Maturation
Lysosomal Lumen Acidification
Central Nervous System Maturation
Rostrocaudal Neural Tube Patterning
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of Transforming Growth Factor Beta1 Production
Neutrophil Degranulation
Regulation Of MAPK Cascade
Eye Pigmentation
Head Morphogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Metabolism of Angiotensinogen to Angiotensins
Neutrophil degranulation
Drugs
Diseases
Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
Cone-rod dystrophy and cone dystrophy, including: Cone-rod dystrophy (CORD); Cone dystrophy (COD); Retinal cone dystrophy (RCD)
Retinitis pigmentosa (RP)
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Metabolite levels (
23823483
)
Interacting Genes
14 interacting genes:
DCTN1
DCTN2
HOMEZ
IFT88
KIF3A
KIFAP3
NPM1
PDE6D
RPGRIP1
SLC25A10
SMC1A
SMC3
TUBG1
YWHAE
19 interacting genes:
ADRA1A
AGT
CD72
CREB3
GLP1R
HTR2C
NKG7
NSG1
PMP22
PTTG1IP
REN
SEC22A
TIMMDC1
TMEM203
TMEM97
UPK2
VAMP5
VKORC1
ZBTB16
Entrez ID
6103
10159
HPRD ID
02425
06454
Ensembl ID
ENSG00000156313
ENSG00000182220
Uniprot IDs
Q92834
O75787
PDB IDs
4JHN
4JHP
4QAM
3LBS
3LC8
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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