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ATP6AP2 and NKG7
Data Source:
BioGRID
(two hybrid)
ATP6AP2
NKG7
Description
ATPase H+ transporting accessory protein 2
natural killer cell granule protein 7
Image
No pdb structure
GO Annotations
Cellular Component
Autophagosome Membrane
Lysosome
Lysosomal Membrane
Endoplasmic Reticulum Membrane
Plasma Membrane
External Side Of Plasma Membrane
Endosome Membrane
Integral Component Of Membrane
Apical Plasma Membrane
Vacuolar Proton-transporting V-type ATPase Complex
Axon
Dendritic Spine Membrane
Cell Body
Postsynaptic Membrane
Extracellular Exosome
Tertiary Granule Membrane
Ficolin-1-rich Granule Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Protein Binding
Signaling Receptor Activity
Protein Binding
Biological Process
Angiotensin Maturation
Lysosomal Lumen Acidification
Central Nervous System Maturation
Rostrocaudal Neural Tube Patterning
Positive Regulation Of Wnt Signaling Pathway
Positive Regulation Of Transforming Growth Factor Beta1 Production
Neutrophil Degranulation
Regulation Of MAPK Cascade
Eye Pigmentation
Head Morphogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Pathways
Metabolism of Angiotensinogen to Angiotensins
Neutrophil degranulation
Drugs
Diseases
Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS)
GWAS
Metabolite levels (
23823483
)
Neutrophil count (
32888494
27863252
)
Neutrophil percentage of white cells (
32888494
)
Interacting Genes
19 interacting genes:
ADRA1A
AGT
CD72
CREB3
GLP1R
HTR2C
NKG7
NSG1
PMP22
PTTG1IP
REN
SEC22A
TIMMDC1
TMEM203
TMEM97
UPK2
VAMP5
VKORC1
ZBTB16
45 interacting genes:
AGTRAP
AMIGO1
AQP6
ARL13B
ATP6AP2
BAMBI
CD53
CD79A
CLDN7
CLEC2D
CLEC4E
CLSTN3
CREB3
EBP
EDA2R
ERGIC3
FAM210B
FFAR2
FNDC9
GJA5
GORAB
GPX8
ISLR2
KLRC1
LHFPL5
LMNA
MFSD6
MGST3
MS4A3
MSR1
MUC1
OPRK1
PEX12
RAMP1
RNF24
SLC18A2
SLC30A8
STOM
STX1A
TLCD4
TMEM106C
TMEM130
TMEM139
TMEM80
TMEM88
Entrez ID
10159
4818
HPRD ID
06454
16188
Ensembl ID
ENSG00000182220
ENSG00000105374
Uniprot IDs
O75787
Q16617
PDB IDs
3LBS
3LC8
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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