ROM1 and PRPH2

Data Source:
HPRD (in vivo, in vitro)

		ROM1	PRPH2
Description		retinal outer segment membrane protein 1	peripherin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane	Photoreceptor Outer Segment Photoreceptor Inner Segment Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein Homodimerization Activity	Protein Binding Protein Homodimerization Activity
	Biological Process	Cell Adhesion Visual Perception Regulation Of Gene Expression Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Camera-type Eye Photoreceptor Cell Differentiation Retina Vasculature Development In Camera-type Eye Protein Localization To Photoreceptor Outer Segment	Cell Adhesion Visual Perception Photoreceptor Cell Outer Segment Organization Detection Of Light Stimulus Involved In Visual Perception Protein Homooligomerization Protein Heterooligomerization Retina Development In Camera-type Eye
Pathways
Drugs
Diseases			Vitelliform macular dystrophy, including: Best disease / Juvenile vitelliform macular dystrophy (VMD2) ; Adult-onset vitelliform macular dystrophy (AVMD) Retinitis pigmentosa (RP) Macular degeneration, including: Age-related macular degeneration (ARMD); Patterned dystrophy of retinal pigment epithelium (PDREP); Retinal macular dystrophy 2 (MCDR2); X-linked atrophic macular degeneration (MDXLA)
GWAS		Serum bilirubin levels in metabolic syndrome ( 30621171) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Pulse pressure ( 27841878)
Interacting Genes		2 interacting genes: ORMDL3 PRPH2	4 interacting genes: CNGB1 GRAP2 PRPH ROM1
Entrez ID		6094	5961
HPRD ID		01616	01553
Ensembl ID		ENSG00000149489	ENSG00000112619
Uniprot IDs		Q03395	P23942
PDB IDs
Enriched GO Terms of Interacting Partners?
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