NIF3L1 and RPIA

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NIF3L1	RPIA
Description		NGG1 interacting factor 3 like 1	ribose 5-phosphate isomerase A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion	Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Transcription Factor Binding Identical Protein Binding	Ribose-5-phosphate Isomerase Activity Protein Binding Identical Protein Binding Monosaccharide Binding
	Biological Process	Neuron Differentiation Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription	D-ribose Metabolic Process Pentose-phosphate Shunt Pentose-phosphate Shunt, Non-oxidative Branch Ribose Phosphate Metabolic Process
Pathways			RPIA deficiency: failed conversion of R5P to RU5P RPIA deficiency: failed conversion of RU5P to R5P Pentose phosphate pathway
Drugs			4-phospho-L-threonic acid
Diseases
GWAS		Triptolide cytotoxicity ( 26121980)	Blood protein levels ( 30072576)
Interacting Genes		93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1	19 interacting genes: ATPAF2 C14orf119 CENPP DDIT4L FOXP2 FXR2 GORASP2 HSPB8 LNX1 NIF3L1 NTAQ1 PCMT1 PICK1 PTPN11 RNF208 SDCBP STK16 TXN2 VTA1
Entrez ID		60491	22934
HPRD ID		10424	01589
Ensembl ID		ENSG00000196290	ENSG00000153574
Uniprot IDs		A0A024R3V5 A0A024R3V7 Q9GZT8	P49247
PDB IDs
Enriched GO Terms of Interacting Partners?
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