RGS4 and UAP1

Data Source:
BioGRID (affinity chromatography technology)

		RGS4	UAP1
Description		regulator of G protein signaling 4	UDP-N-acetylglucosamine pyrophosphorylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Protein-containing Complex	Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	G-protein Alpha-subunit Binding GTPase Activity GTPase Activator Activity Calmodulin Binding	UDP-N-acetylglucosamine Diphosphorylase Activity Carbohydrate Binding Identical Protein Binding UDP-N-acetylgalactosamine Diphosphorylase Activity
	Biological Process	Inactivation Of MAPK Activity Response To Amphetamine G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Heart Rate Response To Cocaine Response To Morphine Positive Regulation Of GTPase Activity Response To Ethanol Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transport Negative Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Actin Filament Organization Negative Regulation Of Glycine Import Across Plasma Membrane Negative Regulation Of Potassium Ion Transmembrane Transport Dorsal Root Ganglion Development Positive Regulation Of Excitatory Postsynaptic Potential	UDP-N-acetylglucosamine Biosynthetic Process
Pathways		G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events	Synthesis of UDP-N-acetyl-glucosamine
Drugs			Uridine-Diphosphate-N-Acetylgalactosamine Uridine-Diphosphate-N-Acetylglucosamine
Diseases
GWAS		Response to fenofibrate (triglyceride levels) ( 27002377) Response to mTOR inhibitor (rapamycin) ( 24009623)
Interacting Genes		13 interacting genes: CALM1 COPB1 COPB2 EGFR ERBB3 GABBR1 GNAI1 GNAI2 GNAO1 GNAQ KRIT1 PLCB1 PTAFR	1 interacting genes: FBXL17
Entrez ID		5999	6675
HPRD ID		03947	04178
Ensembl ID		ENSG00000117152	ENSG00000117143
Uniprot IDs		A0A024R909 P49798	A0A140VKC0 Q16222
PDB IDs			1JV1 1JV3 1JVD 1JVG
Enriched GO Terms of Interacting Partners?
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