RFX4 and RFX2

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		RFX4	RFX2
Description		regulatory factor X4	regulatory factor X2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Chromatin Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telencephalon Development Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Positive Regulation Of Transcription By RNA Polymerase II Cilium Assembly Regulation Of Protein Processing	Acrosome Assembly Regulation Of Transcription By RNA Polymerase II Spermatid Development Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cognitive test performance ( 17903297) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Heart rate ( 23583979) Morning person ( 30696823) Night sleep phenotypes ( 27126917) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Triglyceride levels ( 28334899)	Heel bone mineral density ( 30598549) Mean platelet volume ( 32888494 27863252) Platelet distribution width ( 32888494)
Interacting Genes		3 interacting genes: ESR1 RFX2 RFX3	10 interacting genes: C1orf94 EYA2 FOXJ1 FOXN4 MDFI NFKBID PIAS2 RFX1 RFX4 RFX6
Entrez ID		5992	5990
HPRD ID		04905	00824
Ensembl ID		ENSG00000111783	ENSG00000087903
Uniprot IDs		Q33E94	P48378
PDB IDs
Enriched GO Terms of Interacting Partners?
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