RFC1 and TCEAL1

Data Source:
HPRD (in vivo)

		RFC1	TCEAL1
Description		replication factor C subunit 1	transcription elongation factor A like 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm DNA Replication Factor C Complex Nucleolus Cytoplasm Elg1 RFC-like Complex Extracellular Exosome	Nucleus Nucleoplasm
	Molecular Function	DNA Binding DNA Clamp Loader Activity Double-stranded DNA Binding Protein Binding ATP Binding Enzyme Activator Activity Protein Domain Specific Binding Sequence-specific DNA Binding DNA Clamp Unloader Activity	WW Domain Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA-dependent DNA Replication Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Telomere Maintenance Via Telomerase Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication Nucleotide-excision Repair, DNA Incision Error-prone Translesion Synthesis DNA Damage Response, Detection Of DNA Damage Positive Regulation Of Transcription, DNA-templated Regulation Of Catalytic Activity Error-free Translesion Synthesis DNA Clamp Unloading	Negative Regulation Of Gene Expression
Pathways		Translesion synthesis by REV1 Recognition of DNA damage by PCNA-containing replication complex Translesion Synthesis by POLH Polymerase switching on the C-strand of the telomere PCNA-Dependent Long Patch Base Excision Repair Translesion synthesis by POLK Translesion synthesis by POLI Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Polymerase switching
Drugs
Diseases
GWAS		Asthma ( 30929738) Asthma (adult onset) ( 30929738) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494)
Interacting Genes		19 interacting genes: BRCA1 BRD4 CASP3 CCND1 CDK4 CEBPA CSNK2B HDAC1 MYOC PCNA RELA RFC2 RFC3 SMC1A SSBP3 TCEAL1 UBC YWHAQ ZSCAN1	4 interacting genes: CCNDBP1 HOXB6 RFC1 UBC
Entrez ID		5981	9338
HPRD ID		00024	02211
Ensembl ID		ENSG00000035928	ENSG00000172465
Uniprot IDs		P35251	Q15170
PDB IDs		2EBU 2K6G 2K7F 6VVO
Enriched GO Terms of Interacting Partners?
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