DPF2 and RUBCN

Data Source:
BioGRID (two hybrid)

		DPF2	RUBCN
Description		double PHD fingers 2	rubicon autophagy regulator
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Centrosome Cytosol Intracellular Membrane-bounded Organelle NBAF Complex	Nucleoplasm Lysosome Early Endosome Late Endosome Golgi Apparatus Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Histone Binding Metal Ion Binding H3K9me3 Modified Histone Binding Lysine-acetylated Histone Binding	Protein Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Apoptotic Process Nervous System Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Apoptotic Signaling Pathway Negative Regulation Of Myeloid Progenitor Cell Differentiation	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of Endocytosis Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean spheric corpuscular volume ( 32888494) Urate levels ( 31578528)
Interacting Genes		20 interacting genes: FHL2 GOLGA6L9 H3-4 H3C1 H4C1 HSF2BP LDOC1 LNX1 MEOX2 NFKB2 PICK1 REL RELB RINT1 RUBCN TTC23L TXNDC12 UPF2 ZNF212 ZNF655	15 interacting genes: ANKRD11 BRD1 BYSL DPF2 ENKD1 EXOC1 FAM161A FAM9B GAS8 NME7 SMAD9 TCEANC VEZF1 ZNF250 ZNF648
Entrez ID		5977	9711
HPRD ID		03394	11069
Ensembl ID		ENSG00000133884	ENSG00000145016
Uniprot IDs		A0A024R582 J3KMZ8 Q92785	Q8N4U6 Q92622
PDB IDs		3IUF 5B79 5VDC 6LTH 6LTJ	6WCW
Enriched GO Terms of Interacting Partners?
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