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TMEM35A and CTSA
Data Source:
BioGRID
(two hybrid)
TMEM35A
CTSA
Description
transmembrane protein 35A
cathepsin A
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Peroxisomal Membrane
Integral Component Of Membrane
Cytoplasmic Vesicle
Extracellular Region
Lysosome
Endoplasmic Reticulum
Membrane
Azurophil Granule Lumen
Lysosomal Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Lumenal Side Of Lysosomal Membrane
Molecular Function
Molecular_function
Protein Binding
Carboxypeptidase Activity
Serine-type Carboxypeptidase Activity
Enzyme Activator Activity
Biological Process
Biological_process
Proteolysis
Glycosphingolipid Metabolic Process
Intracellular Protein Transport
Regulation Of Protein Stability
Neutrophil Degranulation
Regulation Of Catalytic Activity
Regulation Of Chaperone-mediated Autophagy
Negative Regulation Of Chaperone-mediated Autophagy
Pathways
Glycosphingolipid metabolism
MHC class II antigen presentation
Sialic acid metabolism
Defective NEU1 causes sialidosis
Neutrophil degranulation
Drugs
Diseases
Galactosialidosis
GWAS
Interacting Genes
32 interacting genes:
ADIPOQ
APP
BET1
C16orf92
CMTM5
COX20
CTSA
CXCL16
CYB5B
EHHADH
FXYD6
GIMAP1
GOSR2
LNPEP
MGLL
ORMDL1
RTP2
RUSF1
THBD
TMEM106C
TMEM120A
TMEM14C
TMEM201
TMEM222
TMEM229B
TMEM243
TMEM42
TRIM55
TRIM63
VAMP1
VAMP3
VAPA
45 interacting genes:
AHNAK2
AQP2
AQP6
ARL13B
ASPH
BSND
CD79A
COQ9
CPLX4
CREB3L1
CSPG5
ERGIC3
FAM209A
FKBP7
FNDC9
GLB1
GORAB
HIBADH
LAMP2
LMNA
LTB4R2
MFSD14B
MGST3
MUC1
MYG1
NEU1
PSCA
REEP4
RHBDD1
RNF122
SAR1A
SGMS2
SIGLEC12
SLC18A1
SLC30A2
SPN
SSMEM1
STX2
THAP4
TMEM139
TMEM154
TMEM237
TMEM31
TMEM35A
TMX2
Entrez ID
59353
5476
HPRD ID
06523
02020
Ensembl ID
ENSG00000126950
ENSG00000064601
Uniprot IDs
Q53FP2
B4E324
P10619
X6R5C5
X6R8A1
PDB IDs
1IVY
3BP4
3BP7
3BXN
4AZ0
4AZ3
4CI9
4CIA
4CIB
4MWS
4MWT
6WIA
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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