RANBP1 and RANGRF

Data Source:
HPRD (in vitro)

		RANBP1	RANGRF
Description		RAN binding protein 1	RAN guanine nucleotide release factor
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Centrosome Cytosol	Nucleus Nucleoplasm Cytoplasm Rough Endoplasmic Reticulum Cytosol Plasma Membrane Caveola Intercalated Disc Perinuclear Region Of Cytoplasm
	Molecular Function	GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding Cadherin Binding	Guanyl-nucleotide Exchange Factor Activity Sodium Channel Regulator Activity Small GTPase Binding Ion Channel Binding
	Biological Process	Signal Transduction Viral Process Positive Regulation Of GTPase Activity Positive Regulation Of Mitotic Centrosome Separation Intracellular Transport	Regulation Of Heart Rate Regulation Of Membrane Depolarization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Exit From Endoplasmic Reticulum Regulation Of Membrane Potential Regulation Of Catalytic Activity Regulation Of Microtubule Nucleation By Ran Protein Signal Transduction Regulation Of Bundle Of His Cell Action Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Protein Localization To Cell Surface Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Rev-mediated nuclear export of HIV RNA	Phase 0 - rapid depolarisation
Drugs		Copper Phenethyl Isothiocyanate
Diseases
GWAS
Interacting Genes		7 interacting genes: CD93 KPNB1 MDM2 NUPR1 RAN RANGRF RCC1	4 interacting genes: PTPN11 RAN RANBP1 ZDHHC17
Entrez ID		5902	29098
HPRD ID		03110	06407
Ensembl ID		ENSG00000099901	ENSG00000108961
Uniprot IDs		A0A140VK94 B3KUP2 B4DE76 D3DX26 F6WQW2 P43487	Q9HD47
PDB IDs		1K5D 1K5G	5YFG
Enriched GO Terms of Interacting Partners?
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