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RANGRF
Description
RAN guanine nucleotide release factor
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Rough Endoplasmic Reticulum
Cytosol
Plasma Membrane
Caveola
Intercalated Disc
Perinuclear Region Of Cytoplasm
Molecular Function
Guanyl-nucleotide Exchange Factor Activity
Sodium Channel Regulator Activity
Small GTPase Binding
Ion Channel Binding
Biological Process
Regulation Of Heart Rate
Regulation Of Membrane Depolarization
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Protein Exit From Endoplasmic Reticulum
Regulation Of Membrane Potential
Regulation Of Catalytic Activity
Regulation Of Microtubule Nucleation By Ran Protein Signal Transduction
Regulation Of Bundle Of His Cell Action Potential
Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction
Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential
Regulation Of Sodium Ion Transmembrane Transport
Positive Regulation Of Protein Localization To Plasma Membrane
Positive Regulation Of Protein Localization To Cell Surface
Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Phase 0 - rapid depolarisation
Drugs
Diseases
GWAS
Interacting Genes
4 interacting genes:
PTPN11
RAN
RANBP1
ZDHHC17
Entrez ID
29098
HPRD ID
06407
Ensembl ID
ENSG00000108961
Uniprot IDs
Q9HD47
PDB IDs
5YFG
Enriched GO Terms of Interacting Partners
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