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RAD9A and OGG1
Data Source:
BioGRID
(pull down)
RAD9A
OGG1
Description
RAD9 checkpoint clamp component A
8-oxoguanine DNA glycosylase
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Checkpoint Clamp Complex
Nucleus
Nucleoplasm
Mitochondrion
Nuclear Matrix
Nuclear Speck
Protein-containing Complex
Molecular Function
Protein Binding
3'-5' Exonuclease Activity
Exodeoxyribonuclease III Activity
SH3 Domain Binding
Enzyme Binding
Protein Kinase Binding
Histone Deacetylase Binding
Damaged DNA Binding
Endonuclease Activity
Protein Binding
Microtubule Binding
Oxidized Purine Nucleobase Lesion DNA N-glycosylase Activity
Oxidized Purine DNA Binding
8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity
Class I DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity
Biological Process
DNA Replication Checkpoint
DNA Damage Checkpoint
DNA Replication
DNA Repair
Cellular Response To DNA Damage Stimulus
Intra-S DNA Damage Checkpoint
Cellular Response To Ionizing Radiation
Nucleic Acid Phosphodiester Bond Hydrolysis
Regulation Of Signal Transduction By P53 Class Mediator
Acute Inflammatory Response
Base-excision Repair
Base-excision Repair, AP Site Formation
Regulation Of Transcription, DNA-templated
Cellular Response To DNA Damage Stimulus
Response To Oxidative Stress
Aging
Response To Radiation
Response To Light Stimulus
Response To Estradiol
Nucleotide-excision Repair, DNA Incision
Response To Drug
Negative Regulation Of Apoptotic Process
Depurination
Depyrimidination
Response To Ethanol
Response To Folic Acid
Cellular Response To Cadmium Ion
Negative Regulation Of Double-strand Break Repair Via Single-strand Annealing
Pathways
Activation of ATR in response to replication stress
HDR through Single Strand Annealing (SSA)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Regulation of TP53 Activity through Phosphorylation
G2/M DNA damage checkpoint
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Displacement of DNA glycosylase by APEX1
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway
Defective OGG1 Substrate Binding
Defective OGG1 Substrate Processing
Drugs
Diseases
GWAS
Body fat distribution (arm fat ratio) (
30664634
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Interacting Genes
38 interacting genes:
ABL1
AR
ATAD5
ATM
BCL2
BCL2L1
CAD
CHEK2
CLSPN
COPS5
CSNK2A1
CSNK2A2
DNAJC7
FEM1B
FEN1
HDAC1
HUS1
HUS1B
ITSN2
MLH1
MSH2
MSH3
MSH6
NR3C1
OGG1
PCNA
POLB
PRKCE
RAD17
RAD9B
RHNO1
RPA1
RPA2
SF3B3
TDG
TLK1
TOPBP1
WRN
6 interacting genes:
CHGB
HUS1
PRKCA
RAD1
RAD9A
XRCC1
Entrez ID
5883
4968
HPRD ID
04788
03582
Ensembl ID
ENSG00000172613
ENSG00000114026
Uniprot IDs
Q99638
E5KPM5
E5KPM6
E5KPM7
E5KPM8
E5KPM9
E5KPN0
E5KPN1
O15527
PDB IDs
3A1J
3G65
3GGR
6HM5
6J8Y
1EBM
1FN7
1HU0
1KO9
1LWV
1LWW
1LWY
1M3H
1M3Q
1N39
1N3A
1N3C
1YQK
1YQL
1YQM
1YQR
2I5W
2NOB
2NOE
2NOF
2NOH
2NOI
2NOL
2NOZ
2XHI
3IH7
3KTU
5AN4
6RLW
6W0M
6W0R
6W13
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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