ZNF71 and FXR1

Data Source:
BioGRID (two hybrid)

		ZNF71	FXR1
Description		zinc finger protein 71	FMR1 autosomal homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleolus Cytoplasm Cytosol Polysome Postsynaptic Density Membrane Axon Growth Cone Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Costamere Dendritic Spine Dendritic Spine Neck Perinuclear Region Of Cytoplasm Presynapse Glutamatergic Synapse Dendritic Filopodium
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding MRNA 3'-UTR Binding Protein Binding RNA Strand Annealing Activity Protein Homodimerization Activity Translation Regulator Activity Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Protein Phosphorylation Apoptotic Process Muscle Organ Development Negative Regulation Of Translation Cell Differentiation Regulation Of MRNA Stability Positive Regulation Of Translation Regulation Of Filopodium Assembly Skeletal Muscle Organ Development Positive Regulation Of Gene Silencing By MiRNA Positive Regulation Of Response To DNA Damage Stimulus
Pathways		Generic Transcription Pathway	Signaling by BRAF and RAF fusions
Drugs
Diseases
GWAS		IgE levels in asthmatics ( 23967269) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Bipolar disorder and eating disorder ( 26433762) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Eating disorder in bipolar disorder ( 26433762) Metabolite levels ( 23823483) Schizophrenia ( 25056061 19571811 29483656 30285260)
Interacting Genes		28 interacting genes: BYSL CSNK2B DVL3 FXR1 KDM1A LGALS14 MAP3K20 MFAP1 PGRMC1 PHF1 PICK1 PLK1 PRKCZ PRPF31 RIN3 SART3 SSX2IP TRIM41 U2AF2 ZBTB24 ZBTB9 ZGPAT ZNF417 ZNF497 ZNF524 ZNF648 ZNF792 ZNF835	48 interacting genes: AP1M1 BLK BYSL C1orf35 CBX8 CCDC187 CDC7 CDKL3 CEP126 CRMP1 CSNK2A1 CWF19L2 CYFIP2 DHX15 ELOA ERCC6 ERG28 ESCO2 FAM161A FAM90A1 FBXO4 FMR1 FXR2 GBP2 HSPB1 KIF9 LNX1 LRIF1 LUC7L2 MAGOH MAGOHB MCRS1 MFAP1 PRAM1 PRPF31 PRSS23 SRPK2 STK16 SUFU SYT6 TBC1D22B TCEA2 TRPM1 YES1 ZMAT2 ZNF417 ZNF438 ZNF71
Entrez ID		58491	8087
HPRD ID		11838	02892
Ensembl ID		ENSG00000197951	ENSG00000114416
Uniprot IDs		Q9NQZ8	A0A0F7KYT8 A0A0F7L1S3 P51114
PDB IDs			2CPQ 3KUF 3O8V
Enriched GO Terms of Interacting Partners?
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