ZNF71 and MFAP1

Data Source:
BioGRID (two hybrid)

		ZNF71	MFAP1
Description		zinc finger protein 71	microfibril associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Microfibril Extracellular Region Nucleus Nucleoplasm U2-type Spliceosomal Complex Centrosome U2-type Precatalytic Spliceosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II	MRNA Splicing, Via Spliceosome
Pathways		Generic Transcription Pathway	Molecules associated with elastic fibres
Drugs
Diseases
GWAS		IgE levels in asthmatics ( 23967269) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Lipoprotein phospholipase A2 activity in cardiovascular disease ( 28753643)
Interacting Genes		28 interacting genes: BYSL CSNK2B DVL3 FXR1 KDM1A LGALS14 MAP3K20 MFAP1 PGRMC1 PHF1 PICK1 PLK1 PRKCZ PRPF31 RIN3 SART3 SSX2IP TRIM41 U2AF2 ZBTB24 ZBTB9 ZGPAT ZNF417 ZNF497 ZNF524 ZNF648 ZNF792 ZNF835	90 interacting genes: ALKBH8 AMOTL2 AP2M1 BEND7 BHLHB9 BICD2 CARD9 CCDC102B CCDC33 CCDC57 CDC14B CDCA7L CEP55 CEP57L1 CEP70 CEP76 COG6 COIL CSNK2A1 DHX38 DHX8 DNTTIP1 FAM9B FRA10AC1 FXR1 FXR2 GAS8 GKAP1 GOLGA2 GOLGA6L9 GRIPAP1 HMBOX1 HOMER3 HOOK2 HSF2BP HSPB1 IK KATNBL1 KIFC3 KLHL2 KRT40 L3MBTL3 LDOC1 LMNA LMNB2 LZTS1 MAD1L1 MCRS1 MID2 MIPOL1 MTUS2 NDC80 NGDN OLIG3 PAX6 PHC2 PIBF1 PIH1D1 PLEKHF2 SART1 SNW1 SSX2IP STAC3 STX11 TADA2A TCP10L TEPSIN TFIP11 THAP1 TLE5 TRAF2 TRIM41 TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB1 ZBTB14 ZBTB8A ZFP1 ZFP41 ZFP64 ZNF398 ZNF41 ZNF558 ZNF620 ZNF71 ZNF76 ZRANB1
Entrez ID		58491	4236
HPRD ID		11838	02569
Ensembl ID		ENSG00000197951	ENSG00000140259
Uniprot IDs		Q9NQZ8	P55081
PDB IDs			5F5S 5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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