PEX2 and PEX10

Data Source:
BioGRID (pull down)
HPRD (in vivo, two hybrid)

		PEX2	PEX10
Description		peroxisomal biogenesis factor 2	peroxisomal biogenesis factor 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisomal Membrane Integral Component Of Peroxisomal Membrane Membrane Cdc73/Paf1 Complex	Peroxisome Peroxisomal Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Very Long-chain Fatty Acid Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination Protein Destabilization Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Ubiquitination
Pathways		E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import Class I peroxisomal membrane protein import	E3 ubiquitin ligases ubiquitinate target proteins Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Fasting plasma glucose ( 31170924) Height ( 20881960 31562340) Infant length ( 25281659) Menarche (age at onset) ( 27182965 25231870) Nicotine dependence ( 28440896) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)	Body mass index ( 26426971) Non-obstructive azoospermia ( 22197933)
Interacting Genes		4 interacting genes: APP ERG28 PEX10 TLE1	10 interacting genes: CGRRF1 HNRNPD LIG4 MKRN3 PCGF6 PEX12 PEX19 PEX2 PEX5 UBE2I
Entrez ID		5828	5192
HPRD ID		01367	04175
Ensembl ID		ENSG00000164751	ENSG00000157911
Uniprot IDs		P28328	A0A024R068 A0A024R0A4 O60683
PDB IDs
Enriched GO Terms of Interacting Partners?
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