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PEX2

Description peroxisomal biogenesis factor 2
Image No pdb structure
GO Annotations Cellular Component
  • Peroxisomal Membrane
  • Integral Component Of Peroxisomal Membrane
  • Membrane
  • Cdc73/Paf1 Complex
Molecular Function
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Very Long-chain Fatty Acid Metabolic Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Protein Targeting To Peroxisome
  • Fatty Acid Beta-oxidation
  • Peroxisome Organization
  • Protein Import Into Peroxisome Matrix
  • Protein Ubiquitination
  • Protein Destabilization
  • Negative Regulation Of Fibroblast Proliferation
  • Negative Regulation Of Epithelial Cell Proliferation
Pathways
  • E3 ubiquitin ligases ubiquitinate target proteins
  • Peroxisomal protein import
  • Peroxisomal protein import
  • Class I peroxisomal membrane protein import
Drugs
Diseases
  • Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
  • Fasting plasma glucose ( 31170924)
  • Height ( 20881960 31562340)
  • Infant length ( 25281659)
  • Menarche (age at onset) ( 27182965 25231870)
  • Nicotine dependence ( 28440896)
  • Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Novel Interacting Genes 2 novel interacting genes: ELOC PLEKHF2
Interacting Genes 4 interacting genes: APP ERG28 PEX10 TLE1
Entrez ID 5828
HPRD ID 01367
Ensembl ID ENSG00000164751
Uniprot IDs P28328
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025