PTPRN and SNX19

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vitro)

		PTPRN	SNX19
Description		protein tyrosine phosphatase receptor type N	sorting nexin 19
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Neuronal Cell Body Perikaryon Axon Terminus Synapse	Cytoplasm Cytoplasmic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding GTPase Binding	Protein Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Response To Reactive Oxygen Species Luteinization Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Peptidyl-tyrosine Dephosphorylation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation	Chondrocyte Differentiation Exocytosis Insulin Secretion Dense Core Granule Maturation
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean reticulocyte volume ( 32888494)	Adult body size ( 32376654) Amyotrophic lateral sclerosis (sporadic) ( 24529757) anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Metabolite levels ( 23823483) Pulse pressure ( 30224653 27841878 30578418) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872)
Interacting Genes		19 interacting genes: CAPN2 CCDC134 CLN8 GJA8 GPR152 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 TIMMDC1 TMEM80 TRDN UBQLN4	2 interacting genes: NOTCH3 PTPRN
Entrez ID		5798	399979
HPRD ID		03466	18621
Ensembl ID		ENSG00000054356	ENSG00000120451
Uniprot IDs		Q16849 Q96IA0	B7ZAU9 E9PJV7 E9PLV3 Q92543
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?
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