PTPRN and TMEM80

Data Source:
BioGRID (two hybrid)

		PTPRN	TMEM80
Description		protein tyrosine phosphatase receptor type N	transmembrane protein 80
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Secretory Granule Transport Vesicle Membrane Neuronal Cell Body Perikaryon Axon Terminus Synapse	Integral Component Of Membrane Ciliary Transition Zone
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding GTPase Binding	Protein Binding
	Biological Process	Response To Reactive Oxygen Species Luteinization Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Peptidyl-tyrosine Dephosphorylation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation	Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Mean reticulocyte volume ( 32888494)
Interacting Genes		19 interacting genes: CAPN2 CCDC134 CLN8 GJA8 GPR152 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 TIMMDC1 TMEM80 TRDN UBQLN4	65 interacting genes: ADGRE2 AGTR1 AIG1 AQP1 ARL6IP6 BET1 BIK C11orf24 C14orf180 C3orf52 C5orf46 CCDC167 CD63 CLDN11 CLDN19 CLDN8 CLDND2 CLEC2D CMTM5 CNIH3 COL4A5 CXCR2 CYBC1 DOLK EMD ERMP1 FAM20B FAM3C FKBP8 FXYD3 GPR37L1 IER3IP1 LAT LSMEM1 MALL MRAP2 NKG7 PRB1 PTPN9 PTPRN RPRM SERP2 SLC30A8 SLC66A2 SMAGP SMCO4 STATH STX7 SYNGR1 TLCD1 TMEM100 TMEM107 TMEM109 TMEM120B TMEM128 TMEM14A TMEM243 TMEM65 TNFRSF10C TRARG1 TSPAN1 TSPO2 TVP23B VKORC1L1 WNT4
Entrez ID		5798	283232
HPRD ID		03466	14143
Ensembl ID		ENSG00000054356	ENSG00000177042
Uniprot IDs		Q16849 Q96IA0	A0A0A0MTU4 B7Z7W9 Q96HE8
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?
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