PTPN3 and AKR1C1

  • Data Source:
  • BioGRID (two hybrid)

PTPN3

AKR1C1

Description protein tyrosine phosphatase non-receptor type 3 aldo-keto reductase family 1 member C1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Estimated glomerular filtration rate ( 31015462)
  • HIV-associated neurocognitive disorder ( 28447399)
  • HIV-associated neurocognitive disorder (asymptomatic neurocogntive impairment) ( 28447399)
  • HIV-associated neurocognitive disorder (mild neurocognitive disorder or asymptomatic neurocognitive impairment) ( 28447399)
  • Iris color (a* coordinate) ( 30895295)
  • Iris color (b* coordinate) ( 30895295)
  • Red blood cell density in sickle cell anemia ( 28552477)
  • Serum albumin level ( 29403010)
  • Staphylococcus aureus nasal carriage (persistent) ( 26569114)
  • Triglyceride levels ( 32203549)
Interacting Genes 26 interacting genes: ADAM17 AKR1C1 AKT1 CD247 DIP2A GHR HSPB1 LMO1 MAPK12 MLH1 MTMR9 NXT2 PLEKHF2 RNF111 RPS6KA1 TENT5D TFAP4 TRIM41 VCP VWA2 WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10 3 interacting genes: COMMD8 MAPK3 PTPN3
Entrez ID 5774 1645
HPRD ID 06767 07194
Ensembl ID ENSG00000070159 ENSG00000187134
Uniprot IDs B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3 Q04828
PDB IDs 2B49 4QUM 4QUN 4RH5 4RH9 4RHG 4RI4 4RI5 4S0G 6HKS 1MRQ 3C3U 3GUG 3NTY 4YVP 6A7A 6IJX
Enriched GO Terms of Interacting Partners?
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