KRT86 and OLIG3

Data Source:
BioGRID (two hybrid)

		KRT86	OLIG3
Description		keratin 86	oligodendrocyte transcription factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytosol Keratin Filament	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Keratinization Cornification	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Spinal Cord Motor Neuron Cell Fate Specification Neuron Differentiation Spinal Cord Motor Neuron Migration
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases		Monilethrix
GWAS		Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)	Asthma ( 30929738) Asthma (childhood onset) ( 30929738) Celiac disease ( 22057235) Celiac disease and Rheumatoid arthritis ( 26546613) Cognitive decline rate in late mild cognitive impairment ( 26252872) Forced expiratory volume in 1 second (occupational environmental exposures interaction) ( 25979521) Hodgkin's lymphoma ( 30194254) Multiple sclerosis ( 31604244 21833088) Primary biliary cholangitis ( 26394269) Rheumatoid arthritis ( 18794853 20453841 17982456) Rheumatoid arthritis (ACPA-positive) ( 24532676) Systemic lupus erythematosus ( 28714469) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Tonsillectomy ( 27182965 28928442)
Interacting Genes		45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655	29 interacting genes: AP1M1 ARID5A ATN1 BYSL CADPS CARD10 CYSRT1 HMG20A KRT86 KRTAP1-1 KRTAP10-8 KRTAP11-1 KRTAP19-2 KRTAP19-5 KRTAP3-2 KRTAP3-3 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-8 MDFI MFAP1 PLAGL2 PROP1 RUNX1 TCF12 TLE5 TRAF1 WWOX
Entrez ID		3892	167826
HPRD ID		03567	17662
Ensembl ID		ENSG00000170442	ENSG00000177468
Uniprot IDs		A8K872 O43790	Q7RTU3
PDB IDs
Enriched GO Terms of Interacting Partners?
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