IFT80 and PLXNA2

Data Source:
HPRD (two hybrid)

		IFT80	PLXNA2
Description		intraflagellar transport 80	plexin A2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cilium Intraciliary Transport Particle B Ciliary Basal Body Ciliary Tip 9+0 Non-motile Cilium	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function		Protein Binding Semaphorin Receptor Activity Identical Protein Binding
	Biological Process	Osteoblast Differentiation Endochondral Ossification Growth Plate Cartilage Chondrocyte Differentiation Smoothened Signaling Pathway Osteoblast Proliferation Bone Mineralization Involved In Bone Maturation Intraciliary Transport Involved In Cilium Assembly Negative Regulation Of Epithelial Cell Proliferation Limb Development Cilium Assembly Articular Cartilage Development Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly Negative Regulation Of Non-canonical Wnt Signaling Pathway	Somitogenesis Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		Intraflagellar transport Intraflagellar transport	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) LDL cholesterol ( 30275531) Malaria ( 31844061)	Adolescent idiopathic scoliosis ( 31417091) Bitter alcoholic beverage consumption ( 31046077) Cardiac hypertrophy ( 21348951) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) General risk tolerance (MTAG) ( 30643258) Lung cancer in never smokers ( 28604730) Manganese levels ( 26025379) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		2 interacting genes: PLXNA2 UBXN10	6 interacting genes: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L
Entrez ID		57560	5362
HPRD ID		13853	03033
Ensembl ID		ENSG00000068885	ENSG00000076356
Uniprot IDs		Q9P2H3	O75051
PDB IDs			3Q3J
Enriched GO Terms of Interacting Partners?
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