SEMA6A and LVRN

Data Source:
BioGRID (two hybrid)

		SEMA6A	LVRN
Description		semaphorin 6A	laeverin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Plasma Membrane Integral Component Of Membrane Axon	Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Semaphorin Receptor Binding Chemorepellent Activity	Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Neural Crest Cell Migration Apoptotic Process Cytoskeleton Organization Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Animal Organ Morphogenesis Negative Regulation Of Angiogenesis Positive Regulation Of Cell Migration Cellular Response To Vascular Endothelial Growth Factor Stimulus Negative Regulation Of Axon Extension Involved In Axon Guidance Negative Chemotaxis Negative Regulation Of ERK1 And ERK2 Cascade Semaphorin-plexin Signaling Pathway Negative Regulation Of Cell Adhesion Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of Sprouting Angiogenesis Positive Regulation Of Neuron Migration	Proteolysis Signal Transduction Regulation Of Blood Pressure Peptide Catabolic Process
Pathways		Other semaphorin interactions
Drugs
Diseases
GWAS		Allergic rhinitis ( 22036096) Amyotrophic lateral sclerosis ( 19451621) Blood protein levels ( 29875488) Body mass index ( 27296613) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823) Cortical surface area (MOSTest) ( 32665545) Eosinophilic esophagitis ( 25017104) High chromosomal aberration frequency (chromatid type) ( 31586183) Periodontitis (DPAL) ( 24024966) Subcortical volume (MOSTest) ( 32665545) Wegener's granulomatosis ( 23740775)	Spontaneous preterm birth without premature rupture of membranes ( 31194736)
Interacting Genes		6 interacting genes: EVL ITSN2 SH3RF1 SORBS1 SORBS2 UBE2I	2 interacting genes: IFIT3 LMNA
Entrez ID		57556	206338
HPRD ID		06906	07118
Ensembl ID		ENSG00000092421	ENSG00000172901
Uniprot IDs		A0A0A0MQU6 Q9H2E6	Q0P5U8 Q6Q4G3
PDB IDs		6WTS
Enriched GO Terms of Interacting Partners?
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