PTK7 and MTMR6

Data Source:
BioGRID (two hybrid)

		PTK7	MTMR6
Description		protein tyrosine kinase 7 (inactive)	myotubularin related protein 6
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Nuclear Envelope Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Membrane Ruffle Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Phosphatidylinositol-3-phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Activity Phosphatidylinositol-3,5-bisphosphate Phosphatase Activity
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Dephosphorylation Phosphatidylinositol Biosynthetic Process Endocytosis Peptidyl-tyrosine Dephosphorylation Phosphatidylinositol Dephosphorylation
Pathways			Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Metabolite levels ( 31628463) Triglyceride levels ( 32203549)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	14 interacting genes: AATK ALKBH4 AMOTL2 ERBB3 ERBB4 LMTK2 MTMR9 MTNR1B MTUS2 NMI PTK7 RARG ROR2 TRIM27
Entrez ID		5754	9107
HPRD ID		03534	11946
Ensembl ID		ENSG00000112655	ENSG00000139505
Uniprot IDs		Q13308	Q9Y217
PDB IDs		6VG3	2YF0
Enriched GO Terms of Interacting Partners?
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