PTK7 and PPM1K

Data Source:
BioGRID (two hybrid)

		PTK7	PPM1K
Description		protein tyrosine kinase 7 (inactive)	protein phosphatase, Mg2+/Mn2+ dependent 1K
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Protein Binding Metal Ion Binding Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Protein Dephosphorylation Branched-chain Amino Acid Catabolic Process
Pathways			Branched-chain amino acid catabolism
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Blood metabolite levels ( 24816252) Branched-chain amino acid levels (Isoleucine) ( 27898682) Branched-chain amino acid levels (Leucine) ( 27898682) Branched-chain amino acid levels (Valine) ( 27898682) Coffee consumption (cups per day) ( 25288136) Conduct disorder (maternal expressed emotions interaction) ( 18846501) Metabolite levels ( 22286219 22916037) Metabolite levels (small molecules and protein measures) ( 27005778) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271) Serum uric acid levels ( 32514006)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	14 interacting genes: AATK BIRC2 ERBB3 HSF2BP HSPB2 LMTK2 MAGEA11 MYB MYO15B NTAQ1 PTK7 UBXN11 XIAP ZNF410
Entrez ID		5754	152926
HPRD ID		03534	15167
Ensembl ID		ENSG00000112655	ENSG00000163644
Uniprot IDs		Q13308	Q8N3J5
PDB IDs		6VG3	2IQ1 4DA1 6AK7
Enriched GO Terms of Interacting Partners?
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