PTK7 and CLIC5

Data Source:
BioGRID (affinity chromatography technology)

		PTK7	CLIC5
Description		protein tyrosine kinase 7 (inactive)	chloride intracellular channel 5
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Focal Adhesion	Golgi Apparatus Microtubule Organizing Center Cell Cortex Actin Cytoskeleton Apical Plasma Membrane Chloride Channel Complex Extracellular Exosome
	Molecular Function	Protein Kinase Activity Protein Binding ATP Binding Cell Adhesion Molecule Binding Coreceptor Activity Involved In Wnt Signaling Pathway, Planar Cell Polarity Pathway	Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Establishment Of Planar Polarity Kidney Development Ventricular Septum Development Axis Elongation Protein Phosphorylation Cell Adhesion Signal Transduction Positive Regulation Of Neuron Projection Development Cell Migration Actin Cytoskeleton Reorganization Wound Healing Establishment Of Epithelial Cell Apical/basal Polarity Convergent Extension Lung-associated Mesenchyme Development Regulation Of Canonical Wnt Signaling Pathway Coronary Vasculature Development Cellular Response To Retinoic Acid Cochlea Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Positive Regulation Of Canonical Wnt Signaling Pathway	Glutathione Metabolic Process Chloride Transport Female Pregnancy Visual Perception Sensory Perception Of Sound Regulation Of Ion Transmembrane Transport Response To Stimulus Chloride Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576 29875488) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Gout (normal type) ( 32238385) Heel bone mineral density ( 30598549) Intraocular pressure ( 29785010) Itch intensity from mosquito bite ( 28199695) Mosquito bite size ( 28199695) Periodontal microbiota ( 22699663)
Interacting Genes		38 interacting genes: CDC14A CLNK CTDSP2 DUSP10 DUSP14 DUSP15 DUSP18 DUSP19 DUSP21 DUSP26 DUSP29 ERBB2 ILKAP KRTAP1-3 KRTAP10-8 MDFI MTMR1 MTMR10 MTMR6 MTMR9 MTUS2 NBPF19 NOTCH2NLA PPM1A PPM1B PPM1F PPM1K PPP3CA PPP3CB PTEN PTPN11 PTPN12 PTPN6 PTPN7 PTPRR STYX TPTE TPTE2	8 interacting genes: ACTA1 ACTN1 EZR GSN IQGAP1 LAMTOR5 SRPK1 TPRN
Entrez ID		5754	53405
HPRD ID		03534	06292
Ensembl ID		ENSG00000112655	ENSG00000112782
Uniprot IDs		Q13308	Q49AE1 Q53G01 Q9NZA1
PDB IDs		6VG3	6Y2H
Enriched GO Terms of Interacting Partners?
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