NLGN4X and CCL22

Data Source:
BioGRID (two hybrid)

		NLGN4X	CCL22
Description		neuroligin 4 X-linked	C-C motif chemokine ligand 22
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane Dendrite Synapse Excitatory Synapse Spanning Component Of Membrane Presynapse Postsynaptic Density Membrane Symmetric, GABA-ergic, Inhibitory Synapse Asymmetric, Glutamatergic, Excitatory Synapse	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Chloride Ion Binding Signaling Receptor Activity Neurexin Family Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding Scaffold Protein Binding	Protein Binding Chemokine Activity CCR Chemokine Receptor Binding
	Biological Process	Brainstem Development Neuron Cell-cell Adhesion Chemical Synaptic Transmission Learning Cerebellum Development Neuron Differentiation Adult Behavior Social Behavior Organ Growth Cell-cell Junction Organization Synaptic Vesicle Endocytosis Modulation Of Chemical Synaptic Transmission Synapse Organization Vocalization Behavior Negative Regulation Of Excitatory Postsynaptic Potential Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Presynapse Assembly	Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor
Pathways		Neurexins and neuroligins Neurexins and neuroligins	Chemokine receptors bind chemokines Interleukin-10 signaling Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS		Metabolite levels ( 23823483) Schizophrenia ( 25056061 29483656)	Asthma ( 32296059) Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 24076602) Systemic lupus erythematosus ( 28714469)
Interacting Genes		2 interacting genes: DLG4 DLGAP2	10 interacting genes: AQP6 CCL14 CCL19 CCR4 CRYAB DPP4 GCLC HERC3 PF4V1 VCAM1
Entrez ID		57502	6367
HPRD ID		02336	04263
Ensembl ID		ENSG00000146938	ENSG00000102962
Uniprot IDs		A0A024RBV0 A8K4S1 B3KP11 Q8N0W4	O00626
PDB IDs		2WQZ 2XB6 3BE8
Enriched GO Terms of Interacting Partners?
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