ISY1 and ACAD9

Data Source:
BioGRID (affinity chromatography technology)

		ISY1	ACAD9
Description		ISY1 splicing factor homolog	acyl-CoA dehydrogenase family member 9
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex Post-spliceosomal Complex	Nucleus Mitochondrion Mitochondrial Inner Membrane Dendrite Mitochondrial Membrane
	Molecular Function	RNA Binding Protein Binding	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription-coupled Nucleotide-excision Repair	Long-chain Fatty Acid Metabolic Process Mitochondrial Respiratory Chain Complex I Assembly Medium-chain Fatty Acid Metabolic Process
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Dental caries ( 23064961) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes		9 interacting genes: CCNC EXOC8 FAM90A1 KDM8 LMO1 LMO2 MLH1 WBP4 XAB2
Entrez ID		57461	28976
HPRD ID		13834	12412
Ensembl ID		ENSG00000240682	ENSG00000177646
Uniprot IDs		Q9ULR0	Q9H845
PDB IDs		5YZG 6FF7 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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