REXO1 and PAFAH1B2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		REXO1	PAFAH1B2
Description		RNA exonuclease 1 homolog	platelet activating factor acetylhydrolase 1b catalytic subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleic Acid Binding Exonuclease Activity	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Nucleic Acid Phosphodiester Bond Hydrolysis	Lipid Metabolic Process Spermatogenesis Brain Development Lipid Catabolic Process Positive Regulation Of Macroautophagy Neutrophil Degranulation
Pathways			Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Body mass index ( 29273807) Essential hypertension (time to event) ( 32589924) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)	Adult body size ( 32376654) Blood protein levels ( 28240269 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		4 interacting genes: ELOA PAFAH1B2 RLIM TCEA1	19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1
Entrez ID		57455	5049
HPRD ID		15478	03940
Ensembl ID		ENSG00000079313	ENSG00000168092
Uniprot IDs		Q8N1G1	P68402 V9HW44
PDB IDs			1VYH
Enriched GO Terms of Interacting Partners?
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