CEMIP and PLXNA2

Data Source:
HPRD (two hybrid)

		CEMIP	PLXNA2
Description		cell migration inducing hyaluronidase 1	plexin A2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Endoplasmic Reticulum Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle Membrane Clathrin-coated Endocytic Vesicle	Semaphorin Receptor Complex Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hyalurononglucosaminidase Activity Protein Binding Hyaluronic Acid Binding Clathrin Heavy Chain Binding ER Retention Sequence Binding	Protein Binding Semaphorin Receptor Activity Identical Protein Binding
	Biological Process	Sensory Perception Of Sound Positive Regulation Of Peptidyl-threonine Phosphorylation Hyaluronan Biosynthetic Process Hyaluronan Catabolic Process Positive Regulation Of Cell Migration Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Protein Kinase C Activity	Somitogenesis Negative Regulation Of Cell Adhesion Regulation Of Cell Shape Neural Tube Development Cerebellar Granule Cell Precursor Tangential Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Centrosome Localization Pharyngeal System Development Limb Bud Formation Semaphorin-plexin Signaling Pathway Semaphorin-plexin Signaling Pathway Involved In Axon Guidance
Pathways		Hyaluronan biosynthesis and export	Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions
Drugs
Diseases
GWAS		Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 30604766) Glomerular filtration rate ( 29403010)	Adolescent idiopathic scoliosis ( 31417091) Bitter alcoholic beverage consumption ( 31046077) Cardiac hypertrophy ( 21348951) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) General risk tolerance (MTAG) ( 30643258) Lung cancer in never smokers ( 28604730) Manganese levels ( 26025379) Pursuit maintenance gain ( 29064472) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Squamous cell lung carcinoma ( 28604730)
Interacting Genes		1 interacting genes: PLXNA2	6 interacting genes: CEMIP DHX37 FNBP4 HACE1 IFT80 UBAP2L
Entrez ID		57214	5362
HPRD ID		10519	03033
Ensembl ID		ENSG00000103888	ENSG00000076356
Uniprot IDs		Q8WUJ3	O75051
PDB IDs			3Q3J
Enriched GO Terms of Interacting Partners?
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