ZMIZ1 and CACHD1

Data Source:
HPRD (two hybrid)

		ZMIZ1	CACHD1
Description		zinc finger MIZ-type containing 1	cache domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Voltage-gated Calcium Channel Complex
	Molecular Function	Transcription Coactivator Activity Zinc Ion Binding Nuclear Receptor Coactivator Activity SMAD Binding	Voltage-gated Calcium Channel Activity
	Biological Process	Vasculogenesis In Utero Embryonic Development Heart Morphogenesis Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Vitellogenesis Cell Aging Pyramidal Neuron Migration Androgen Receptor Signaling Pathway Regulation Of Protein Sumoylation Positive Regulation Of T Cell Differentiation Positive Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription Positive Regulation Of Fibroblast Proliferation Developmental Growth Artery Morphogenesis SMAD Protein Signal Transduction Positive Regulation Of Nucleic Acid-templated Transcription	Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Ankylosing spondylitis ( 23749187) Apolipoprotein A1 levels ( 32203549) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Autoimmune traits (pleiotropy) ( 30572963) Bipolar disorder ( 20351715) Blond vs. brown/black hair color ( 30531825) Breast cancer ( 23535729 20453838) Brown vs. black hair color ( 30531825) Celiac disease ( 22057235 20190752 25920553 30572963) Ceramide levels (C24:0) ( 32489964) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Cobalt levels ( 26025379) Colorectal cancer ( 30529582 24836286) Colorectal cancer or advanced adenoma ( 30510241) Crohn's disease ( 25489960 28067908 21102463) Crohn's disease and psoriasis ( 22482804) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Granulocyte count ( 27863252) HDL cholesterol levels ( 32203549) Height ( 25282103 25429064 23563607 31562340) High density lipoprotein cholesterol levels ( 31928498) Inflammatory bowel disease ( 28067908) Inflammatory bowel disease (early onset) ( 19915574) Lymphocyte counts ( 32888494) Lymphocyte percentage of white cells ( 32888494 27863252) Marginal zone lymphoma or multiple sclerosis ( 31407831) Mean platelet volume ( 32888494) Medication use (drugs used in diabetes) ( 31015401) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Multiple sclerosis ( 31604244 22190364 24076602 19525953 21833088) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494 27863252) Pediatric autoimmune diseases ( 26301688) Platelet distribution width ( 32888494 27863252) PR interval ( 32439900) Prostate cancer ( 31562322) Psoriasis ( 25854761 23143594) Psoriasis vulgaris ( 26626624) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) TPE interval (resting) ( 32386560) Triiodothyronine/thyroxine ratio ( 30824882) Type 2 diabetes ( 22885922 24509480 30054458 29358691 30297969 26818947 31118516 32499647 30718926 28869590) Urate levels ( 31578528) Vitiligo ( 20526339) Waist circumference ( 28552196) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)	Gut microbiota relative abundance (Bifidobacterium) ( 33208821)
Interacting Genes		5 interacting genes: AR CACHD1 CNTNAP2 PIAS3 TBC1D4	5 interacting genes: BICRAL PEBP1 RANBP10 XAB2 ZMIZ1
Entrez ID		57178	57685
HPRD ID		12115	13874
Ensembl ID		ENSG00000108175	ENSG00000158966
Uniprot IDs		A0A024QZN6 A0JLS3 Q9ULJ6	A0A0A0MQY7 A0A3B3ISH2 Q5VU97
PDB IDs		5AIZ
Enriched GO Terms of Interacting Partners?
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