GJC2 and LTB4R2

Data Source:
BioGRID (two hybrid)

		GJC2	LTB4R2
Description		gap junction protein gamma 2	leukotriene B4 receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Gap Junction Connexin Complex Integral Component Of Membrane Paranode Region Of Axon Perikaryon Myelin Sheath Proximal Neuron Projection	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	Gap Junction Channel Activity Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Regulation Of Protein Phosphorylation Cell-cell Signaling Brain Development Response To Toxic Substance Positive Regulation Of Gene Expression Cell Communication By Electrical Coupling Transmembrane Transport Positive Regulation Of Oligodendrocyte Progenitor Proliferation Positive Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Chemotaxis Inflammatory Response G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Gap junction assembly	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases		Hypomyelinating leukodystrophy (HLD); Pelizaeus-Merzbacher disease (PMD)
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		6 interacting genes: ADRB2 CHRM2 F2RL1 GPR35 LTB4R2 PTGER4	46 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MYO1E OBSL1 P4HTM PER1 PIGM PKD1 RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		57165	56413
HPRD ID		10582	16153
Ensembl ID		ENSG00000198835	ENSG00000213906
Uniprot IDs		A0A654IBV7 Q5T442	B4E292 Q9NPC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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