PITHD1 and SUMO4

Data Source:
HPRD (in vivo)

		PITHD1	SUMO4
Description		PITH domain containing 1	small ubiquitin like modifier 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Sperm Cytoplasmic Droplet	Nucleus SUMO Ligase Complex
	Molecular Function		Molecular_function Protein Tag Ubiquitin-like Protein Ligase Binding
	Biological Process	Spermatid Development Penetration Of Zona Pellucida Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Regulation Of Proteasomal Protein Catabolic Process Penetration Of Cumulus Oophorus	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 27863252)	Dupuytren's disease ( 28886342)
Interacting Genes		2 interacting genes: CDC73 SUMO4	75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		57095	387082
HPRD ID		13717	10584
Ensembl ID		ENSG00000057757	ENSG00000177688
Uniprot IDs		B4DKP7 Q9GZP4	Q6EEV6
PDB IDs
Enriched GO Terms of Interacting Partners?
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