PLSCR3 and TNIP3

Data Source:
BioGRID (two hybrid)

		PLSCR3	TNIP3
Description		phospholipid scramblase 3	TNFAIP3 interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Cytosol Plasma Membrane Integral Component Of Membrane	Cytosol
	Molecular Function	Magnesium Ion Binding Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Lead Ion Binding Protein Self-association Mercury Ion Binding Calcium-dependent Protein Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Apoptotic Process Plasma Membrane Phospholipid Scrambling Cardiolipin Biosynthetic Process Glucose Homeostasis Cholesterol Homeostasis Regulation Of Apoptotic Process Cellular Response To Lipopolysaccharide Regulation Of Release Of Cytochrome C From Mitochondria	MyD88-independent Toll-like Receptor Signaling Pathway Inflammatory Response Protein Deubiquitination Toll-like Receptor 4 Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Lipopolysaccharide
Pathways			Ovarian tumor domain proteases
Drugs
Diseases
GWAS			Breast cancer ( 23468962) Multiple sclerosis ( 31604244)
Interacting Genes		34 interacting genes: AIPL1 C10orf55 C19orf54 C22orf39 CATSPER1 COL8A1 HOXA1 INCA1 KRTAP11-1 KRTAP15-1 KRTAP19-6 KRTAP19-7 KRTAP3-2 KRTAP3-3 KRTAP6-1 LCE1C LCE2B LCE4A LCE5A MAPKBP1 NAA10 NXPE2 PITX1 PLSCR1 PRKCD RUNX1T1 S100A7L2 SMCP STK16 TNIP3 TNS2 TRIP13 WWOX ZIC1	27 interacting genes: CCN3 CYSRT1 DAZAP2 FAM161A KPNA3 KRT40 KRTAP10-3 KRTAP10-8 LITAF LZTS2 MAGEA2 MAGEA2B MTUS2 NBPF19 NOTCH2NLA NTAQ1 PIBF1 PLSCR3 TAX1BP1 TCEANC TNFAIP3 TNIP1 TRIM55 TRIM63 TRIM8 UBC ZBTB8A
Entrez ID		57048	79931
HPRD ID		07400	16268
Ensembl ID		ENSG00000187838	ENSG00000050730
Uniprot IDs		Q9NRY6	Q96KP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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