TOM1L1 and PWP2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	PWP2
Description		target of myb1 like 1 membrane trafficking protein	PWP2 small subunit processome component
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Membrane Extracellular Exosome	Nucleoplasm Small-subunit Processome Pwp2p-containing Subcomplex Of 90S Preribosome
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding	RNA Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Ribosomal Small Subunit Assembly Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		29 interacting genes: AMFR CCDC47 CELF1 COPS7A CWF19L1 DNAJB13 FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TASOR TOLLIP TSG101 TUBA1B UBC UBXN4 VAV2 VCP	4 interacting genes: DCAF7 MAPT MTDH TOM1L1
Entrez ID		10040	5822
HPRD ID		05266	03279
Ensembl ID		ENSG00000141198	ENSG00000241945
Uniprot IDs		O75674 Q8NI65	Q15269
PDB IDs		3RRU
Enriched GO Terms of Interacting Partners?
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