NPY1R and NPY

Data Source:
HPRD (in vivo)

		NPY1R	NPY
Description		neuropeptide Y receptor Y1	neuropeptide Y
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Region Extracellular Space Golgi Apparatus Synapse Neuronal Dense Core Vesicle
	Molecular Function	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity Protein Binding	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Signaling Receptor Binding Hormone Activity Neuropeptide Hormone Activity Calcium Channel Regulator Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Outflow Tract Morphogenesis Glucose Metabolic Process G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotory Behavior Feeding Behavior Regulation Of Blood Pressure Sensory Perception Of Pain Regulation Of Multicellular Organism Growth	G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Neuropeptide Signaling Pathway Chemical Synaptic Transmission Feeding Behavior Regulation Of Blood Pressure Adult Feeding Behavior Central Nervous System Neuron Development Cerebral Cortex Development Neuron Projection Development Positive Regulation Of Appetite Intestinal Epithelial Cell Differentiation
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs		Peptide YY (3-36)	Phentermine 2-aminoisobutyric acid L-tyrosinamide
Diseases
GWAS		Erythrocyte cadmium concentration ( 27005419) Lung cancer ( 28604730) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)	Adult body size ( 32376654) Aggressive periodontitis (sex interaction) ( 25256105) Body size at age 10 ( 32376654) Chronotype ( 30696823) Morning person ( 30696823) Periodontitis ( 23459936) Vitamin D levels ( 25208829)
Interacting Genes		4 interacting genes: ATP13A2 LSM7 NPY PYY	16 interacting genes: ATP12A BAG6 GHRL MC4R MEP1A MEP1B NPFF NPFFR2 NPY1R NPY2R NPY4R NPY5R NR1H2 PMCH UBQLN1 UBQLN2
Entrez ID		4886	4852
HPRD ID		01215	01214
Ensembl ID		ENSG00000164128	ENSG00000122585
Uniprot IDs		P25929	A4D158 P01303
PDB IDs		2F1U 2IIL 5ZBQ	1QFA 1RON
Enriched GO Terms of Interacting Partners?
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