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SHD and CAPN10
Data Source:
BioGRID
(two hybrid)
SHD
CAPN10
Description
Src homology 2 domain containing transforming protein D
calpain 10
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Cytosol
Plasma Membrane
Molecular Function
Phosphotyrosine Residue Binding
Protein Binding
SNARE Binding
Calcium-dependent Cysteine-type Endopeptidase Activity
Protein Binding
Cytoskeletal Protein Binding
Biological Process
Proteolysis
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Actin Cytoskeleton Reorganization
Positive Regulation Of Insulin Secretion
Positive Regulation Of Intracellular Transport
Cellular Response To Insulin Stimulus
Positive Regulation Of Glucose Import
Type B Pancreatic Cell Apoptotic Process
Positive Regulation Of Type B Pancreatic Cell Apoptotic Process
Pathways
Degradation of the extracellular matrix
Drugs
Diseases
Type II diabetes mellitus
GWAS
Interacting Genes
14 interacting genes:
ABL1
BECN1
CAPN10
EGFR
ERBB2
ERBB3
ERBB4
KRTCAP2
MET
MRPS22
NCK2
OLIG1
OSBPL6
PSG11
5 interacting genes:
EFNB1
FANCC
FLOT1
PSMA7
SHD
Entrez ID
56961
11132
HPRD ID
15337
05595
Ensembl ID
ENSG00000105251
ENSG00000142330
Uniprot IDs
Q96IW2
Q9HC96
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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