PRTFDC1 and GPR158

Data Source:
BioGRID (enzymatic study, pull down, affinity chromatography technology, enzymatic study, enzymatic study, enzymatic study, enzymatic study, pull down, enzymatic study, x-ray crystallography, enzymatic study, enzymatic study, x-ray crystallography, affinity chromatography technology)
HPRD (in vitro)

		PRTFDC1	GPR158
Description		phosphoribosyl transferase domain containing 1	G protein-coupled receptor 158
Image			No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Magnesium Ion Binding Hypoxanthine Phosphoribosyltransferase Activity Protein Binding Protein Homodimerization Activity	G Protein-coupled Receptor Activity
	Biological Process	Purine Ribonucleoside Salvage Guanine Salvage GMP Catabolic Process	G Protein-coupled Receptor Signaling Pathway Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Diisocyanate-induced asthma ( 25918132) Eosinophil counts ( 32888494) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Intraocular pressure ( 29617998) Lymphocyte counts ( 32888494 27863252) Metabolite levels (Pyroglutamine) ( 23934736) Monocyte count ( 32888494 27863252) Myeloid white cell count ( 27863252) Neutrophil count ( 32888494 27863252) Obesity-related traits ( 23251661) Perceived intensity of neohesperidin dihydrochalcone ( 31005972) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494) Plateletcrit ( 32888494 27863252) Post-traumatic stress disorder ( 25456346) Red cell distribution width ( 32888494 27863252) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494 27863252)	Carboplatin disposition in epthelial ovarian cancer ( 29367611) Central corneal thickness ( 32528159) Cerebellum white matter volume ( 31530798) Diverticular disease ( 30177863 30661054) Energy expenditure (24h) ( 28476931) Hepatitis C (spontaneous viral clearance) ( 30593799) Immune response to smallpox vaccine (IL-6) ( 22542470) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998 29235454) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Interacting Genes		19 interacting genes: CNRIP1 DTNB EEF2KMT EPM2AIP1 EWSR1 FLAD1 GNPDA1 HPRT1 LGALS9B LNX1 MCMBP NIF3L1 NTAQ1 SIK1B SPG21 STAT5A TCL1A TMEM14B VWA5A
Entrez ID		56952	57512
HPRD ID		17917	13601
Ensembl ID		ENSG00000099256	ENSG00000151025
Uniprot IDs		Q9NRG1	Q5T848
PDB IDs		2JBH
Enriched GO Terms of Interacting Partners?
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