LGALS14 and FCHO1

Data Source:
BioGRID (two hybrid)

		LGALS14	FCHO1
Description		galectin 14	FCH and mu domain containing endocytic adaptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Clathrin-coated Vesicle
	Molecular Function	Protein Binding Carbohydrate Binding	Protein Binding AP-2 Adaptor Complex Binding
	Biological Process	Apoptotic Process Positive Regulation Of T Cell Apoptotic Process	Clathrin Coat Assembly Membrane Organization Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Sum eosinophil basophil counts ( 27863252)	Basophil count ( 32888494) Coronary artery disease ( 29212778) Monocyte percentage of white cells ( 32888494)
Interacting Genes		46 interacting genes: ADAMTSL4 AJUBA BANP BLZF1 C1QTNF2 COG6 CRLF3 DDIT4L DOK6 FCHO1 FLACC1 FLNA GFAP IKZF3 IL16 JRK KRT19 KRT35 LNX1 LNX2 MEI4 MID2 NFKBID PCBD2 PICK1 POF1B PPM1J REL RIMBP3C SDCBP2 SH3GLB2 SPAG5 STAT5B TARS3 TBC1D25 TCF4 TEKT1 TEPSIN TNR TRIM23 TRIM27 VIM ZBTB8A ZNF438 ZNF655 ZNF71	51 interacting genes: ACVR1 APP BYSL CCDC13 CSNK2A1 CWF19L2 DAB2 DDX6 DNAJC5 ELOA EPS15 EPS15L1 EXOSC5 FBXL7 GRB7 GUCD1 ITSN1 KAT5 KPRP KRTAP10-1 KRTAP10-5 KRTAP13-2 KRTAP13-4 KRTAP15-1 KRTAP4-12 KRTAP6-1 KRTAP6-3 LGALS14 MAB21L3 NCK1 PCGF1 PHETA1 PHLDA2 PICALM PLAC8 PLSCR4 PRPF3 PRPH PTK6 SH2D4A SMURF1 SRPK2 SYTL4 TCEA2 TCEANC TGFB1 TRIM42 TSPAN4 ZBTB16 ZBTB24 ZNF688
Entrez ID		56891	23149
HPRD ID		06268	16887
Ensembl ID		ENSG00000006659	ENSG00000130475
Uniprot IDs		Q8TCE9	A0A0C3SFZ9 B7ZAZ3 O14526
PDB IDs		6K2Y 6K2Z
Enriched GO Terms of Interacting Partners?
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