JPH1 and GPR42

Data Source:
BioGRID (two hybrid)

		JPH1	GPR42
Description		junctophilin 1	G protein-coupled receptor 42
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex	Integral Component Of Plasma Membrane
	Molecular Function	Molecular_function Protein Binding Structural Constituent Of Muscle	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Muscle Organ Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium Ion Transport Into Cytosol	G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) Uterine fibroids ( 28836065)
Interacting Genes		15 interacting genes: AQP6 EDDM3B EMP1 GPR42 HTATIP2 LEPROTL1 MEOX2 NAT8 PLP1 SLC16A13 STRIT1 TMEM120B TMEM65 TTN UACA	104 interacting genes: ADIPOQ ALOX5AP ANKRD46 APOD ATP13A1 ATP4B ATP6V0B ATP6V0C BNIP3 BTN2A2 C1GALT1 CCDC167 CCL4L2 CD300C CD79A CLCA4 CLEC2D COMT CTXN3 CXCL16 CXCL9 DRAM1 EFNA5 EMP1 ERMP1 FAM3C FXYD3 FXYD6 GJB2 GOSR2 GPR37L1 GYPC IER3IP1 IGFBP5 IL1RL1 ITGAM JPH1 KCNA1 KLRG1 LAT LEPROTL1 LHFPL5 LNPEP LTC4S MFSD5 MFSD6 MGAM MS4A1 NDUFB11 NINJ2 NRM NSG1 PAEP PLP1 PLPP1 PMP22 PNLIPRP1 RPRM RTP2 RUSF1 SCD SERINC1 SERP2 SERTM1 SLC30A2 SLC30A3 SLC30A8 SLC35E4 SLC38A1 SLC38A7 SLC39A2 SLC41A1 SLC41A2 SMCO4 SMIM3 STATH STRIT1 STX8 SYNDIG1 SYNGR1 TEX264 TF TM4SF4 TMBIM6 TMEM140 TMEM147 TMEM182 TMEM19 TMEM237 TMEM239 TMEM242 TMEM262 TMEM30B TMEM60 TMEM65 TRARG1 TREX1 TSPO2 YIF1A YIPF1 YIPF2 YIPF4 YIPF6 ZFPL1
Entrez ID		56704	2866
HPRD ID		07286	16033
Ensembl ID		ENSG00000104369	ENSG00000126251
Uniprot IDs		Q7Z682 Q86VR1 Q9HDC5	A0A0K0PUY3 O15529
PDB IDs
Enriched GO Terms of Interacting Partners?
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