TRIM39 and UBXN7

Data Source:
BioGRID (two hybrid)

		TRIM39	UBXN7
Description		tripartite motif containing 39	UBX domain protein 7
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol	Nucleoplasm Cytosol Nuclear Body VCP-NPL4-UFD1 AAA ATPase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Identical Protein Binding Ubiquitin Protein Ligase Activity	Protein Binding Transcription Factor Binding Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process	Apoptotic Process Mitotic G2 DNA Damage Checkpoint Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Protein Stabilization Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway	Post-translational Protein Modification
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Neddylation
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Neuroticism ( 29255261)	Adult body size ( 32376654) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) IgM levels ( 28628107)
Interacting Genes		61 interacting genes: APP CACTIN CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 GAMT HINFP KDM1A LMNA LNX1 LXN MED18 MNAT1 MTURN OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMB1 PSMD9 RAD23A RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBL5 UBTD1 UBTD2 UBXN1 UBXN6 UBXN7 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26	24 interacting genes: APP CLEC19A CRX CYSRT1 DAZAP2 FAM168A MAP3K1 MEOX1 MUL1 NEDD8 NFYC PAX5 PAX6 REL SMURF1 TRAF6 TRIM39 TRIM62 TRIM8 UBC UBQLN1 UBQLN2 VCP ZNRF1
Entrez ID		56658	26043
HPRD ID		09298	19396
Ensembl ID		ENSG00000204599	ENSG00000163960
Uniprot IDs		A0A024RCP5 A0A024RCR1 Q9HCM9	O94888
PDB IDs		2DID 2DIF 2ECJ	1WJ4 2DAL 2DLX 5X3P 5X4L
Enriched GO Terms of Interacting Partners?
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