PSD and GLRA2

Data Source:
HPRD (two hybrid)

		PSD	GLRA2
Description		pleckstrin and Sec7 domain containing	glycine receptor alpha 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cleavage Furrow Ruffle Membrane Dendritic Spine Extrinsic Component Of Postsynaptic Endosome Membrane Postsynaptic Density, Intracellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glycinergic Synapse
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phospholipid Binding	Transmembrane Signaling Receptor Activity Chloride Channel Activity Glycine Binding Extracellularly Glycine-gated Chloride Channel Activity Glycine-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Metal Ion Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential
	Biological Process	Signal Transduction Neuron Projection Development Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity	Signal Transduction Neuropeptide Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Response To Amino Acid Nervous System Process Synaptic Transmission, Glycinergic Excitatory Postsynaptic Potential Cellular Response To Amino Acid Stimulus Cellular Response To Zinc Ion Cellular Response To Ethanol Chloride Transmembrane Transport
Pathways			Neurotransmitter receptors and postsynaptic signal transmission Neurotransmitter receptors and postsynaptic signal transmission
Drugs			Glycine Lindane Picrotoxin Ethanol Memantine Taurine
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: GLRA2 GMFG GNB5 HEXD RAB40C	5 interacting genes: BAG6 DDX24 GDI2 PSD SEC23A
Entrez ID		5662	2742
HPRD ID		09085	02379
Ensembl ID		ENSG00000059915	ENSG00000101958
Uniprot IDs		A5PKW4 Q86YI3	P23416
PDB IDs
Enriched GO Terms of Interacting Partners?
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