GLRA2 and PSD

Data Source:
HPRD (two hybrid)

		GLRA2	PSD
Description		glycine receptor alpha 2	pleckstrin and Sec7 domain containing
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Chloride Channel Complex Neuron Projection Synapse Postsynaptic Membrane Glycinergic Synapse	Cleavage Furrow Ruffle Membrane Dendritic Spine Extrinsic Component Of Postsynaptic Endosome Membrane Postsynaptic Density, Intracellular Component
	Molecular Function	Transmembrane Signaling Receptor Activity Chloride Channel Activity Glycine Binding Extracellularly Glycine-gated Chloride Channel Activity Glycine-gated Chloride Ion Channel Activity Neurotransmitter Receptor Activity Metal Ion Binding Transmitter-gated Ion Channel Activity Involved In Regulation Of Postsynaptic Membrane Potential	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phospholipid Binding
	Biological Process	Signal Transduction Neuropeptide Signaling Pathway Chemical Synaptic Transmission Ion Transmembrane Transport Regulation Of Membrane Potential Response To Amino Acid Nervous System Process Synaptic Transmission, Glycinergic Excitatory Postsynaptic Potential Cellular Response To Amino Acid Stimulus Cellular Response To Zinc Ion Cellular Response To Ethanol Chloride Transmembrane Transport	Signal Transduction Neuron Projection Development Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways		Neurotransmitter receptors and postsynaptic signal transmission Neurotransmitter receptors and postsynaptic signal transmission
Drugs		Glycine Lindane Picrotoxin Ethanol Memantine Taurine
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: BAG6 DDX24 GDI2 PSD SEC23A	5 interacting genes: GLRA2 GMFG GNB5 HEXD RAB40C
Entrez ID		2742	5662
HPRD ID		02379	09085
Ensembl ID		ENSG00000101958	ENSG00000059915
Uniprot IDs		P23416	A5PKW4 Q86YI3
PDB IDs
Enriched GO Terms of Interacting Partners?
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