PRPS2 and PRPSAP1

Data Source:
HPRD (in vivo, in vitro)

		PRPS2	PRPSAP1
Description		phosphoribosyl pyrophosphate synthetase 2	phosphoribosyl pyrophosphate synthetase associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex Cytoplasm	Ribose Phosphate Diphosphokinase Complex Cytoplasm
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Protein Binding ATP Binding AMP Binding Kinase Activity GDP Binding Carbohydrate Binding Identical Protein Binding Protein Homodimerization Activity ADP Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Protein Binding Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process AMP Biosynthetic Process Nucleoside Metabolic Process Phosphorylation Animal Organ Regeneration	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Negative Regulation Of Catalytic Activity
Pathways		5-Phosphoribose 1-diphosphate biosynthesis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Systemic lupus erythematosus ( 26606652)	High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)
Interacting Genes		4 interacting genes: NOTCH2NLA NTAQ1 PRPSAP1 PRPSAP2	9 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 PRPSAP2 UBE2I
Entrez ID		5634	5635
HPRD ID		02414	03151
Ensembl ID		ENSG00000101911	ENSG00000161542
Uniprot IDs		A0A140VK41 P11908	B4DP31 Q14558
PDB IDs			2C4K
Enriched GO Terms of Interacting Partners?
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