RNF20 and PA2G4

Data Source:
BioGRID (enzymatic study, affinity chromatography technology, imaging technique, affinity chromatography technology)

		RNF20	PA2G4
Description		ring finger protein 20	proliferation-associated 2G4
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus HULC Complex	Extracellular Region Nucleus Nucleolus Cytoplasm Membrane Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Binding Histone Binding Identical Protein Binding Metal Ion Binding	Nucleic Acid Binding Transcription Corepressor Activity RNA Binding Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Negative Regulation Of Cell Migration Positive Regulation Of Histone Methylation Histone H2B Ubiquitination Positive Regulation Of Transcription, DNA-templated Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Histone H2B Ubiquitination	RRNA Processing Regulation Of Translation Negative Regulation Of Apoptotic Process Neutrophil Degranulation Positive Regulation Of Cell Differentiation Negative Regulation Of Transcription, DNA-templated
Pathways		E3 ubiquitin ligases ubiquitinate target proteins	Neutrophil degranulation
Drugs
Diseases
GWAS			Adult body size ( 32376654) Allergic disease (asthma, hay fever or eczema) ( 29785011) Anorexia nervosa ( 28494655) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Refractive error ( 32231278) Vitiligo ( 22951725)
Interacting Genes		36 interacting genes: AMOTL2 ATM BAG4 C1orf109 CDC73 FBXO7 FGFR4 H2AC18 H2AC20 H2BC21 H2BC3 H3C14 H4C14 HSF1 HTT ITSN2 KIF11 MSL1 NCBP1 PA2G4 PAF1 PRPF8 RB1CC1 RNF40 SMURF2 SUMO2 TACC3 TRIM14 UBE2A UBE2B UBE2D2 UBE2E1 UBE2L3 USHBP1 XRCC3 ZDHHC17	21 interacting genes: AR ATR ERBB3 ESR1 EXOSC5 HDAC2 HMGA1 HMGA2 HSPA4 IKBKG LIG4 MTOR PRKCA PRKCB PRKCG RB1 RNF20 SIN3A STUB1 SUMO4 TERF1
Entrez ID		56254	5036
HPRD ID		07410	03685
Ensembl ID		ENSG00000155827	ENSG00000170515
Uniprot IDs		Q5VTR2	A0A024RB85 Q9UQ80
PDB IDs		5TRB	2Q8K 3J2I 6CHT 6LSR 6SXO 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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