ANKH and RPSA

Data Source:
BioGRID (two hybrid)

		ANKH	RPSA
Description		ANKH inorganic pyrophosphate transport regulator	ribosomal protein SA
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane Outer Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Cytosolic Small Ribosomal Subunit Extracellular Exosome
	Molecular Function	Inorganic Phosphate Transmembrane Transporter Activity Phosphate Ion Transmembrane Transporter Activity Inorganic Diphosphate Transmembrane Transporter Activity	Virus Receptor Activity RNA Binding Structural Constituent Of Ribosome Laminin Receptor Activity Protein Binding Ribosome Binding Laminin Binding
	Biological Process	Skeletal System Development Locomotory Behavior Regulation Of Bone Mineralization Inorganic Diphosphate Transport Phosphate Ion Transmembrane Transport Transmembrane Transport	Ribosomal Small Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Cell Adhesion Viral Transcription Viral Entry Into Host Cell
Pathways		Miscellaneous transport and binding events	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs			Tigapotide Copper
Diseases		Craniometaphyseal dysplasia
GWAS		Asthma ( 31959851) Blood metabolite levels ( 24816252) Glaucoma ( 31959993 30054594) Glaucoma (primary open-angle) ( 29891935) Homeostasis model assessment of insulin resistance (dietary factor interaction) ( 24204828) Intraocular pressure ( 29785010 31959993 30054594) Response to fenofibrate (total cholesterol levels) ( 27002377) Type 2 diabetes ( 30054458 30297969 29632382 32499647) Type 2 diabetes (adjusted for BMI) ( 29632382) Type 2 diabetes (time to event) ( 32589924) Urate levels (BMI interaction) ( 25811787)	Dentate gyrus volume x schizophrenia interaction ( 31155012)
Interacting Genes		2 interacting genes: APOE RPSA	31 interacting genes: ABCD1 ACADVL ACD ANKH CALM2 CBX5 CCDC13 CLEC4G CSF2RA DCTN6 GNMT HBG2 HNRNPD HSPB1 IL7R ILRUN ITGA6 KARS1 LAMA2 LINC01554 NKX3-1 PEA15 POT1 PRND PROS1 RNF114 RPS21 SLC2A5 SUMO4 TINF2 TRIB3
Entrez ID		56172	3921
HPRD ID		05509	01038
Ensembl ID		ENSG00000154122	ENSG00000168028
Uniprot IDs		Q9HCJ1	A0A024R2L6 A0A0C4DG17 P08865
PDB IDs			3BCH 4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBD 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 6ZVJ 7A09 7K5I
Enriched GO Terms of Interacting Partners?
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