NSMCE3 and NSMCE1

Data Source:
BioGRID (pull down)

		NSMCE3	NSMCE1
Description		NSE3 homolog, SMC5-SMC6 complex component	NSE1 homolog, SMC5-SMC6 complex component
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleoplasm Cytoplasm Smc5-Smc6 Complex	Chromosome, Telomeric Region Nucleus Nucleoplasm Smc5-Smc6 Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein Dimerization Activity	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Protein Dimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	DNA Repair DNA Recombination Positive Regulation Of Protein Ubiquitination Cellular Response To UV Regulation Of Growth Cellular Response To Radiation Cellular Response To Hydroxyurea	Double-strand Break Repair Via Homologous Recombination Postreplication Repair Protein Ubiquitination Intracellular Signal Transduction Positive Regulation Of Response To DNA Damage Stimulus
Pathways		SUMOylation of DNA damage response and repair proteins	SUMOylation of DNA damage response and repair proteins
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29679657) Asthma ( 31959851 31619474) Gut microbiota (bacterial taxa) ( 27723756) Medication use (adrenergics, inhalants) ( 31015401) Night sleep phenotypes ( 27126917) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
Interacting Genes		4 interacting genes: E2F1 NGFR NSMCE1 TRIM28	5 interacting genes: ERBB3 MAGEF1 NSMCE3 UBC UBE2D2
Entrez ID		56160	197370
HPRD ID		10503	17648
Ensembl ID		ENSG00000185115	ENSG00000169189
Uniprot IDs		Q96MG7	Q8WV22
PDB IDs		5HVQ 5WY5	2CT0 5HVQ 5WY5
Enriched GO Terms of Interacting Partners?
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