ACOT13 and MYDGF

Data Source:
BioGRID (two hybrid)

		ACOT13	MYDGF
Description		acyl-CoA thioesterase 13	myeloid derived growth factor
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GO Annotations	Cellular Component	Nucleus Mitochondrion Spindle Cytosol	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus
	Molecular Function	Protein Binding Palmitoyl-CoA Hydrolase Activity Metal Ion Binding Acyl-CoA Hydrolase Activity Myristoyl-CoA Hydrolase Activity	Protein Binding
	Biological Process	Acyl-CoA Metabolic Process Protein Homotetramerization Negative Regulation Of Cold-induced Thermogenesis	Angiogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Endothelial Cell Proliferation Apoptotic Process Positive Regulation Of Phosphatidylinositol 3-kinase Signaling IRE1-mediated Unfolded Protein Response Negative Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Kinase B Signaling
Pathways		Mitochondrial Fatty Acid Beta-Oxidation	XBP1(S) activates chaperone genes
Drugs		2-Undecanone
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		4 interacting genes: MYDGF NTAQ1 RBBP6 SPG21	13 interacting genes: ACOT13 BAG6 EIF3F HPCA HPCAL1 LCN2 MDM2 NCALD SGTA SGTB UBQLN1 UBQLN2 UBQLN4
Entrez ID		55856	56005
HPRD ID		07158	08415
Ensembl ID		ENSG00000112304	ENSG00000074842
Uniprot IDs		Q9NPJ3	Q969H8
PDB IDs		2F0X 2H4U 3F5O	6O6W 6SVK 6SVL
Enriched GO Terms of Interacting Partners?
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